Gilbert has appeared on The Simpsons, 24, Will & Grace, Law & Order: Special Victims Unit and Private Practice.Starting in 2004, she had a recurring role as smart but sarcastic medical student Jane Figler on the long-running hospital drama ER; her appearances spanned seasons 11-13.Sara Gilbert says that she realized she was a lesbian after making out with actor Johnny Galecki.And years down the line, Galecki said he'd still be happy to hold her hand. The revelation came Thursday on "The Talk," where all week the cohosts have been sharing well-kept secrets. Sara Gilbert says that she realized she was a lesbian after making out with actor Johnny Galecki.Sara Gilbert and Linda Perry have welcomed their first child together, a son.The baby, Rhodes Emilio Gilbert Perry, was born on Saturday, "The Talk" co-host Julie Chen announced Monday on the show, where Alyssa Milano was filling Gilbert's chair."Both mother and child are doing well," Chen said.Gilbert rose to fame on the hit TV series, "Roseanne," and Perry is the former lead singer for 4 Non Blondes and a music producer, who's been behind big hits for Gwen Stefani, Christina Aguilera and Adam Lambert.
Gilbert won a Daytime Emmy in 2016 for Outstanding Entertainment Talk Show as producer and creator of the show.
Gilbert will reprise the role in 2018 for an eight episode revival.
Her mother is the daughter of The Honeymooners creator Harry Crane. Her two older siblings on her mother's side, Melissa Gilbert and Jonathan Gilbert, were stars of Little House on the Prairie.
She also had a recurring role on the short-lived CBS sitcom The Class as Fern Velch.
From 2007 to 2010, Gilbert appeared in episodes of the CBS TV series The Big Bang Theory as Leslie Winkle, a scientist friend of Leonard Hofstadter played by Johnny Galecki, who had previously played Gilbert's love interest David Healy on Roseanne.